报告内容简介：

Catalyst design for asymmetric synthesis has generally been done by combining relatively strong intermolecular forces, such as coordinative interactions, hydrogen-bonding interactions, and electrostatic interactions, with repulsive forces called as steric repulsions. On the other hand, recent advancement of computational chemistry has revealed the importance of weak intermolecular forces such as C–H···O hydrogen-bonding and London dispersion, which have not been considered before. As a result, more advanced catalyst design based on the synergistic effect of multiple intermolecular forces including these weak intermolecular forces has become possible, making catalysts more enzyme-like. In this lecture, we will discuss synergistic effects of intermolecular forces in our study of asymmetric catalysis.

报告人简介:

Masaya Sawamura

Affiliation: Professor

Department of Chemistry, Faculty of Science, Hokkaido University

Education:

1980-1984 Department of Synthetic Chemistry, Faculty of Engineering, Kyoto University

Awarded the degree of B. of Engineering under supervision of Professor Tatsuya Shono

1984-1989 Department of Synthetic Chemistry, Graduate School of Engineering, Kyoto University

1989  Awarded the degree of Dr. of Engineering under supervision of Professor Yoshihiko Ito

Research Experience:

1993-1994 Visiting Researcher at Harvard University (U.S.A.): Professor Stuart L. Schreiber

Professional Experience:

1989-1995 Assistant Professor, Kyoto University (Prof. Yoshihiko Ito)

1995 Assistant Professor, Tokyo Institute of Technology (Prof. Eiichi Nakamura)

1995-1996 Assistant Professor, The University of Tokyo (Prof. E. Nakamura)

1996-1997 Lecturer, The University of Tokyo

1997-2001 Associate Professor, The University of Tokyo

2001-  Professor, Department of Chemistry, Faculty of Science, Hokkaido University

2016-2022 Hokkaido University Distinguished Professor

Honorary Posts:

1996-1998 The Journal of Synthetic Organic Chemistry, Japan: Associate Editor

2002-2004 Chemistry and Chemical Industry, Japan: Associate Editor

2002-2006 Chemistry Letters: Associate Editor

2012-present Research Advisor, Molecular Technology and Creation of New Function, JST-PRESTO

2015-present Tetrahedron/Tetrahedron Letters, Consulting Editor

Selected Awards:

1. The Chemical Society of Japan Award for Young Chemists (1996)

2. Asian Core Program Lectureship Award (2008)

3. The Chemical Society of Japan Award for Creative Works (2012)

4. Asian Core Program Lectureship Award (2012)

5. Asian Core Program Lectureship Award (2013)

6. SSOJ Nissan Chemical Industries Award for Novel Reaction & Method 2014 (2015)

7. Nagoya Silver Medal (2017)

8. Negishi Award (2018)

9. Synthetic Organic Chemistry Award (2019)

10. The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology (MEXT) - Awards for Science and Technology-Research Category (2021)

Research Interests:

Synthetic Organic Chemistry, Development of New Catalysts and Organic Reactions